Chlamydia, Gonorrhea, Chancroid, Trichomoniasis, bacterial vaginosis (BV), and Genital Herpes std treatment is indicated for sex partners if the last sexual encounter was within 60 days. std treatment of Chlamydia is indicated for patients being treated for Gonorrhea, and vice versa. (It is common to have these two STD infections together) If STD diagnosis is not confirmed, then empiric triple antibiotic std treatment is advocated for the most common STDs - chlamydia treatment, gonorrhea, and trichomoniasis. Triple STD antibiotic regimen: Doxycycline 100 mg twice a day / 10 days; Cipro XR 500mg or 1000mg one single dose (or Levaquin, or Tequin); and Metronidazole 500 mg twice a day for 10 days.
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doxycycline is a member of the tetracycline antibiotics group and is commonly used to treat a variety of infections. doxycycline is a semi-synthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc. and marketed under the brand name Vibramycin. Vibramycin received FDA approval in 1967, becoming Pfizer's first once-a-day broad-spectrum antibiotic. Other brand names include Monodox, Periostat, Vibra-Tabs, Doryx, Vibrox, Adoxa, Doxyhexal and Atridox (topical doxycycline hyclate for Periodontitis).
Metronidazole is a nitroimidazole anti-infective medication used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. It is marketed by Pfizer under the trade name Flagyl in the US, while Sanofi-Aventis markets metronidazole globally under the same tradename, Flagyl, and also by various generic manufacturers, who sell it at a lower price. metronidazole is also used as a gel preparation in the treatment of the dermatological conditions such as rosacea (Rozex and Metro-Gel by Galderma) and fungating tumours (Anabact, Cambridge Healthcare Supplies).
Metronidazole is a prodrug. It is converted in anaerobic organisms by the redox enzyme pyruvate-ferredoxin oxidoreductase. The nitro group of metronidazole is chemically reduced by ferredoxin (or a ferredoxin-linked metabolic process) and the products are responsible for disrupting the DNA helical structure, thus inhibiting nucleic acid synthesis.
Metronidazole is selectively taken up by anaerobic bacteria and sensitive protozoal organisms because of the ability of these organisms to reduce metronidazole to its active form intracellularly.
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Ciprofloxacin (aka cipro) is the generic international name for the synthetic antibiotic manufactured and sold by Bayer A.G. under the brand names cipro, ciproxin and ciprobay (and other brand names in other markets, e.g. veterinary medicine), belonging to a group called fluoroquinolones. Ciprofloxacin (cipro) is bacteriocidal. Its mode of action depends upon blocking bacterial DNA replication by binding itself to an enzyme called DNA gyrase, thereby causing double-stranded breaks in the bacterial chromosome.
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